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Question:

If gentamicin is available in 80 mg/2 ml vials, how many vials are needed to compound an IV bag containing 480 mg of gentamicin?

A 6 vials

explanation

480 mg gentamicin x 2ml/80 mg gentamicin x 1 vial/2ml 12 ml x 1 vial/2 ml = 6 vials

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If octreotide is available in 1000 mcg/5ml vials, how many milliliters are needed to compound an IV bag containing 600 mcg?

3 ml

600 mcg x 5 ml/1000 mcg = 3 ml

During non-sterile compounding, when should you put on all Personal Protective Equipment (PPE)?

after all formulas and calculations are completed

These steps describe the process for non-sterile compounding:
1. Using the prescription, create a formula for the intended product including any calculations and specific amounts of ingredients needed.
2. Wash hands and put on all required PPE.
3. Obtain any hardware supplies such as a balance or graduated cylinder.
4. Weigh/measure out all ingredients using the proper measurement tools.
5. Following the recipe, combine the ingredients in the correct ratios and in the proper order.
6. Document the exact amounts used and label the final product including final strengths of ingredients.

What type of agent increases the viscosity of a suspension?

Thickening agent

A thickening agent makes a suspension viscous or thicker. An emulsifier stabilizes an emulsion. A flocculating agent prevents the clumping together of particles. A mucilage is a glue-like substance.

Which of the following is not an advantage of a solid dosage form?

Takes a longer time for the medication to take effect

An oral solid dosage form takes longer to be absorbed into the body than other oral dosage forms.

How many people should be involved in the compounding process of a single prescription?

one

To ensure safety, only one person should be involved in compounding a single product.

Which dosage form may be prepared by either compressing or molding?

Tablet

A tablet is prepared either by compressing or by molding. The dosage form is accurate, com- pact, portable, and easy to administer.

Which of the following is not a universal precaution?

Wearing jewelry while preparing IV admixtures

USP ,797. prohibits that jewelry be worn when compounding sterile products.

Which of these is required to be documented for all compounded products?

the lot number

These need to be documented for all compounded products:
+ Product names and amount/strength of each used including how compound was mixed
+ A product specific lot number
+ The name of all the people preparing the compound (e.g., technicians and pharmacist who checks it)
+ Date of preparation
+ Storage requirements
+ Beyond-use dating
+ Labeling requirements for all prescriptions

If two drugs are taken together and one of them intensifies the action of the other, what type of drug interaction has occurred?

Potentiation

Antagonism is when two drugs work against each other. Synergism is when the effect of two drugs together is greater than the sum of their individual effects. Additive Effect is when the effect of two drugs together is equal to the sum of their individual effects.

What type of laminar flow hood can be converted to a type B3 hood?

Type A hood

A type A hood recirculates a portion of the air (after it first passes through a HEPA filter) within the hood and exhausts a portion of this air back into the parenteral room. A type A laminar flow hood can be converted to a type B hood.

If you plan to run a dose of medication over 12 hours, how many total milliliters are needed for the infusion to run 1 ml/minute?

720 ml

12 hours x 60 min /1 hour x 1 ml/ min = 720 ml

Which type of dispersion is similar to an ointment but contains more solid materials?

Gel

A gel is a two-phase system containing an extremely fine solid particle that, when mixed, it is difficult to distinguish between the two phases, and it is considered a semisolid form.

Which of the following represents intravenous feeding?

Total parenteral nutrition

Total parenteral nutrition is introduced into the body through an IV line; enteral nutrition provides food through a tube placed in the nose, the stomach, or the small intestine; and oral nutrition occurs through the placement of food in the mouth and traveling through the digestive system.

What type of environment should a laminar flow hood provide?

ISO 5, formerly known as a Class 100 area

Laminar flow hoods should be in a class 100 area, where there are no more than 100 particles that are 0.5 micron or larger per cubic foot of air. The number indicates the number of particles 0.5 micron or larger per cubic foot of air.

Which types of substances require a SDS (formerly known as MSDS)?

Hazardous drugs and chemicals

OSHA requires that all hazardous drugs and chemical have an SDS.