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Question:

Which of these is true regarding opening an ampule during sterile compounding?

A The neck of the ampule should be swabbed with 70% isopropyl alcohol prior to breaking it.
Explaination

To open an ampule, follow these steps:
1. Swab the ampule with 70% isopropyl alcohol especially in the neck (thinnest) area.
2. Covering the ampule with an alcohol swab, grip the top of the ampule and bottom of the ampule with the thumb and index finger of each hand (one hand on top, the other on the bottom).
3. With a quick motion, snap the ampule at the neck being careful not to break it toward the HEPA filter (break toward the side of the hood).